Jennylyn Mercado as Rhodora/Roxanne – Rhodora, as a young girl, experienced extreme physical and emotional abuse when she was abducted and taken away from her family. This experience eventually led her to develop another “persona” inside of her. When she was saved and gets reunited with her family, her split personality disorder starts to manifest. Rhodora’s alter ego, Roxanne starts to emerge.
Roxanne is a confident and smart woman but also scheming and manipulative. She hates her sister Angela so much to the point that she will do everything to get what Angela has – the affection of their mother and Angela’s love, Joaquin.
Yasmien Kurdi as Angela – She blamed herself when her sister Rhodora was kidnapped. But when Rhodora finally gets reunited with them, she was entrapped by the schemes of Roxanne, Rhodora’s alter ego, and was put to jail.
Mark Herras as Joaquin – He is Angela’s fiance. He was shocked when Angela allegedly killed his secretary out of jealousy. Thus, their wedding was cancelled. It was only Rhodora who was there for him in this trying time and because of her presence, he falls for Rhodora and marries her. Little did he know that Rhodora has a split personality and that the alter ego Roxanne was the one who framed Angela’s “murder.”
Mark Anthony Fernandez as Nico – He owns the ancestral home where Angela ended up. He feels for Angela since he also has a grudge against Joaquin’s family and eventually falls in love with her. When Angela is finally free, he is the one who will help get her life back on tract and both of them plan revenge against Rhodora and Joaquin.
Gardo Versoza as Derrick – the doting father of Rhodora and Angela;
Glydel Mercado as Lourdes – the loving and affectionate mother of Rhodora and Angela.
Irma Adlawan as Dr. Vivian – the doctor who diagnosed Rhodora’s illness.
Frank Magalona as Santi – the cousin and best friend of Joaquin.
Lollie Mara as Donya Cita – the owner of a big shipyard company and grandmother of Joaquin.
Vaness del Moral as Pia – the cousin of Angela and Rhodora, she is also Angela’s best friend.
Ms. Boots Anson Roa as Panchang – the grandmother of Rhodora and Angela and the one who had doubts about Rhodora’s return.